Our Viewpoint
We recommend BOTOX® as an adjunct therapy for patients who develop vulvodynia or pelvic floor muscle spasms as a result of chronic pain from endometriosis. We understand that the pelvic floor is affected by the long-term ramifications of massive inflammation from endometriosis lesions. The Endometriosis Treatment Center of America recommends BOTOX for patients with documented pelvic muscle spasticity and focal trigger-point tenderness.

Relevance
Even with complete excision of endometriosis, long-term inflammation that has acted as the ideology for pelvic floor muscle spasticity must be addressed to decrease symptoms of vulvodynia, improve chronic pelvic pain, and improve a patient’s sexual relationship via the decrease in vaginismus associated with spastic pelvic musculature.
- https://rapm.bmj.com/content/early/2019/07/08/rapm-2019-100529 (opens in new tab)
- https://pubmed.ncbi.nlm.nih.gov/19622971/ (opens in new tab)
- https://pubmed.ncbi.nlm.nih.gov/20168100/ (opens in new tab)
- https://pubmed.ncbi.nlm.nih.gov/19694687/ (opens in new tab)
- https://pubmed.ncbi.nlm.nih.gov/30617506/ (opens in new tab)
- https://pubmed.ncbi.nlm.nih.gov/32654386/ (opens in new tab)

